SCHEMBL22307403

SCHEMBL22307403

CNC(NCc1ccccc1)=C(C#N)C#N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 3/20 0.46
LMNA P02545 2/20 0.44
PLIN1 O60240 1/20 0.44
PLIN5 Q00G26 1/20 0.44
ABHD5 Q8WTS1 1/20 0.44
ALOX12 P18054 3/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
GAA P10253 2/20 0.43
POLB P06746 1/20 0.43
IDO1 P14902 1/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22306441 0.79 ALDH1A1 (0.46) KDM4EHPGDLMNAALDH1A1MEN1
SCHEMBL22306421 0.79 HPGD (0.51) MCL1MAPTKDM4ECYP3A4HPGD
SCHEMBL22307392 0.75 MCL1 (0.50) MCL1MAPTHPGDLMNAPLIN1
SCHEMBL6187669 0.75 IDO1 (0.53) MCL1MAPTKDM4ECYP3A4HPGD
SCHEMBL17763698 0.74 MCL1 (0.61) MCL1MAPTKDM4ECYP3A4HPGD
SCHEMBL17763697 0.74 MCL1 (0.61) MCL1MAPTKDM4ECYP3A4HPGD
SCHEMBL17814271 0.74 MCL1 (0.61) MCL1MAPTKDM4ECYP3A4HPGD
SCHEMBL13626330 0.73 PKM (0.41) MCL1MAPTHPGDLMNAPLIN1
N-Benzylmethylamine SCHEMBL28767722 0.73 MAPT (0.77) MCL1MAPTKDM4ECYP3A4HPGD
SCHEMBL24797746 0.71 MCL1 (0.46) MCL1MAPTKDM4ECYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020156298-A1 APPLICATION OF MALONONITRILE COMPOUND AS BACTERICIDE 沈阳化工大学 2020-08-06 WO disclosed