Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067490 | 0.81 | APP (0.56) | — | |
| SCHEMBL22290869 | 0.78 | ALDH1A1 (0.48) | ADORA1ADORA2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL24163735 | 0.77 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL13325756 | 0.75 | NPC1 (0.64) | ADORA1ADORA2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13325790 | 0.73 | ALDH1A3 (0.59) | ADORA1ADORA2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL25919738 | 0.73 | ADORA2A (0.47) | ADORA1ADORA2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4837433 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL22369826 | 0.72 | KDM4E (0.37) | ADORA1ADORA2AKDM4ENPC1RAB9A | |
| SCHEMBL31071672 | 0.72 | NPC1 (0.63) | ADORA1ADORA2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13325903 | 0.70 | ALDH1A1 (0.94) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230029009-A1 | CHEMICAL COMPOUNDS | BLUE OWL CAPITAL CORPORATION, AS NEW AGENT | 2023-01-26 | — | — | US | disclosed |
| US-11459331-B2 | Chemical compounds | AVISTA PHARMA SOLUTIONS, INC. (US) | 2022-10-04 | — | — | US | disclosed |
| US-20200270257-A1 | Chemical Compounds | BLUE OWL CAPITAL CORPORATION, AS NEW AGENT | 2020-08-27 | — | — | US | disclosed |
| WO-2020160075-A1 | CHEMICAL COMPOUNDS | AVISTA PHARMA SOLUTIONS, INC. (US) | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11459331-B2 | Chemical compounds | PTGER4, PTGES, PTGES2 | ADORA1 287/4885ADORA2A 114/4885ALDH1A1 1265/4885 |
| US-20230029009-A1 | CHEMICAL COMPOUNDS | PTGER4, PTGES, PTGES2 | ADORA1 287/4885ADORA2A 114/4885ALDH1A1 1265/4885 |
| US-20200270257-A1 | Chemical Compounds | PTGER4, PTGES, PTGES2 | ADORA1 287/4885ADORA2A 114/4885ALDH1A1 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.