Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31521803 | 0.80 | MMP2 (0.39) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL22307190 | 0.80 | MMP2 (0.39) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29473086 | 0.80 | MMP2 (0.39) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL22308214 | 0.78 | HPGD (0.36) | PTGESRAB9ANPC1CYP1A2S1PR1 | |
| SCHEMBL22307226 | 0.77 | CDK9 (0.36) | RAB9ANPC1MAPTCYP1A2KDM4E | |
| SCHEMBL29473228 | 0.77 | CDK9 (0.36) | RAB9ANPC1MAPTCYP1A2KDM4E | |
| SCHEMBL29473070 | 0.71 | HPGD (0.34) | RAB9ANPC1CYP1A2S1PR1SMN1; SMN2 | |
| SCHEMBL22307222 | 0.71 | HPGD (0.34) | RAB9ANPC1CYP1A2S1PR1SMN1; SMN2 | |
| SCHEMBL3707021 | 0.71 | CA12 (0.42) | SIRT2PKN1PKN2SIRT1SIRT3 | |
| SCHEMBL13830587 | 0.70 | TP53 (0.50) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156323-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-08-06 | — | — | WO | disclosed |