Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.42 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22308838 | 0.96 | HPGD (0.42) | HPGDXDHPDE3BPDE3ACTSS | |
| SCHEMBL22307805 | 0.85 | PDE3B (0.40) | XDHPDE3BPDE3ACTSSCTSK | |
| SCHEMBL22307809 | 0.85 | PDE3B (0.40) | XDHPDE3BPDE3ACTSSCTSK | |
| SCHEMBL22307810 | 0.84 | CTSS (0.46) | PDE3BPDE3ACTSSCTSK | |
| SCHEMBL22307799 | 0.83 | PDE3B (0.55) | XDHPDE3BPDE3ACTSSCTSK | |
| SCHEMBL22309158 | 0.83 | PDE3B (0.56) | PDE3BPDE3ACTSSCTSKAAK1 | |
| SCHEMBL22307812 | 0.83 | PDE3B (0.50) | PDE3BPDE3ACTSSCTSKAAK1 | |
| SCHEMBL22309142 | 0.83 | XDH (0.49) | XDHPDE3BPDE3AAAK1 | |
| SCHEMBL22309147 | 0.82 | S1PR1 (0.46) | PDE3BPDE3ACTSSSYKHTR2C | |
| SCHEMBL22309160 | 0.81 | PDE3B (0.40) | PDE3BPDE3ACTSSCTSKSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020157189-A1 | 1,2,4-TRIAZIN-6(1H)-ONE COMPOUNDS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-06 | — | — | WO | disclosed |