Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800584 | 0.83 | CES1 (0.65) | CES1HDAC1CA2MAPTALDH1A1 | |
| SCHEMBL31208574 | 0.83 | CES1 (0.65) | CES1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL13268944 | 0.83 | CES1 (0.65) | CES1CA1CA2MAPTALDH1A1 | |
| SCHEMBL11492544 | 0.81 | CES1 (0.62) | CES1HDAC1CA1CA2MAPT | |
| SCHEMBL10816935 | 0.81 | CES1 (0.62) | CES1CA1CA2MAPTALDH1A1 | |
| SCHEMBL18790471 | 0.81 | CES1 (0.62) | CES1CA1CA2MLYCDMAPT | |
| SCHEMBL10299600 | 0.81 | CES1 (0.62) | CES1CA1CA2MAPTALDH1A1 | |
| SCHEMBL275573 | 0.79 | CES1 (0.59) | CES1MAPTALDH1A1LMNAALOX15 | |
| SCHEMBL21784944 | 0.79 | CES1 (0.59) | CES1CA1CA2ALDH1A1LMNA | |
| SCHEMBL16788942 | 0.79 | CES1 (0.59) | CES1HDAC1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200247916-A1 | BENZIL MONOKETALS AND THE USE THEREOF | MERCK PATENT GMBH (DE) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247916-A1 | BENZIL MONOKETALS AND THE USE THEREOF | BCKDK, PKLR, BPHL | CES1 1215/4885HDAC1 1998/4885CA1 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.