SCHEMBL22310501

SCHEMBL22310501

Nc1ccc(C(=O)Oc2ccc(-c3ccc(N)cc3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 7/20 0.65
F2 P00734 3/20 0.65
PRSS2 P07478 3/20 0.65
PRSS3 P35030 3/20 0.65
KMT2A Q03164 2/20 0.65
PKM P14618 1/20 0.65
PARP10 Q53GL7 2/20 0.55
NR1H4 Q96RI1 1/20 0.54
HSD17B10 Q99714 2/20 0.52
HGFAC Q04756 2/20 0.49
LMNA P02545 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP3A4 P08684 2/20 0.48
MAOA P21397 1/20 0.48
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
CYP2C19 P33261 1/20 0.47
PDE4D Q08499 1/20 0.47
ACR P10323 5/20 0.46
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3143505 1.00 PRSS1 (0.65) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL10021501 1.00 PRSS1 (0.65) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL107649 0.94 PRSS1 (0.71) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL347429 0.94 PRSS1 (0.71) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL346698 0.94 PRSS1 (0.71) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL9128037 0.93 F2 (0.58) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL28858885 0.93 HSD17B10 (0.59) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL3136588 0.93 PARP10 (0.62) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL23085069 0.91 PRSS1 (0.59) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL3144272 0.91 KMT2A (0.56) PRSS1F2PRSS2PRSS3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020158818-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME 日産化学株式会社 2020-08-06 WO disclosed