SCHEMBL347429

SCHEMBL347429

Nc1ccc(OC(=O)c2ccc(N)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 8/20 0.71
F2 P00734 3/20 0.71
PRSS2 P07478 3/20 0.71
PRSS3 P35030 3/20 0.71
KMT2A Q03164 2/20 0.71
PKM P14618 1/20 0.71
PARP10 Q53GL7 2/20 0.60
NR1H4 Q96RI1 1/20 0.58
HSD17B10 Q99714 1/20 0.57
LMNA P02545 2/20 0.53
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 2/20 0.53
MAOA P21397 1/20 0.53
HGFAC Q04756 2/20 0.53
CYP2C9 P11712 1/20 0.52
TSHR P16473 1/20 0.52
CYP2C19 P33261 1/20 0.52
PDE4D Q08499 1/20 0.52
ACR P10323 6/20 0.50
MEN1 O00255 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346698 1.00 PRSS1 (0.71) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL107649 1.00 PRSS1 (0.71) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL3143505 0.94 PRSS1 (0.65) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL28283207 0.94 PRSS1 (0.65) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL22310501 0.94 PRSS1 (0.65) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL10021501 0.94 PRSS1 (0.65) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL9148082 0.92 PARP10 (0.68) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL8585571 0.92 PRSS1 (0.63) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL9003587 0.92 PRSS1 (0.63) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL9003865 0.92 F2 (0.63) PRSS1F2PRSS2PRSS3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049190-A1 HEAT-RESISTANT LIQUID CRYSTAL POLYMER FILM TAIMIDE TECHNOLOGY INCORPORATION (TW) 2026-02-19 US claimed
US-20250359435-A1 DISPLAY APPARATUS AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2025-11-20 US claimed
EP-4628461-A1 POLY(AMIC ACID) SLURRY FOR OPTICAL FIBERS, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Ningbo Boya Poly Advanced Materials Co., Ltd. (CN) 2025-10-08 EP claimed
US-12378412-B2 Resin composition and article made therefrom Elite Material Co., Ltd. (TW) 2025-08-05 US claimed
CN-120082031-A Shape memory polyimide block copolymer precursor, preparation method thereof and application thereof in 3D printing 江南大学 2025-06-03 CN claimed
WO-2025105900-A1 LOW DIELECTRIC POLYIMIDE FILM USING MONOMER HAVING ESTER GROUP AND MANUFACTURING METHOD THEREOF 피아이첨단소재 주식회사 2025-05-22 WO claimed
CN-115989265-B Polyamic acid composition, polyimide film, laminate, method for producing laminate, and electronic device 株式会社钟化 2025-05-16 CN claimed
CN-119978369-A Polyimide film for optical fiber and preparation method thereof 宁波博雅聚力新材料科技有限公司 2025-05-13 CN claimed
US-20250130495-A1 POLYBENZOXAZOL PRECURSOR OR POLYIMIDE PRECURSOR OR THE COPOLYMER THEREOF, AND POSITIVE PHOTOSENSITIVE RESIN COMPOSITION THEREFROM DUK SAN NEOLUX CO., LTD. (KR) 2025-04-24 US claimed
CN-116178715-B Method for preparing hierarchical polyimide material by hydrothermal polymerization 复旦大学 2025-03-18 CN claimed
CN-102364397-B Radiation-sensitive resin composition, cured film, method for forming cured film, and display device JSR CORP 2015-04-01 CN claimed
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US claimed
US-5399655-A Acid-labile poly(amic acetal ester) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-21 US claimed
US-4736015-A FROM DI-(ORTETRA) ESTER OF BENZHYDROL 3,3*,4,4*-TETRACARBOXYLIC ACID AND AROMATIC DIAMINE INSTITUT FRANCAIS DU PETROLE (FR) 1988-04-05 US claimed
US-4720539-A Polyimide precursor compositions, their manufacture, the resultant polyimides and their use, particularly for manufacturing enamelling varnishes for electric wires CENTRE D'ETUDES DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1988-01-19 US claimed
US-4526835-A Prepreg resin sheets formed by impregnating reinforcing substrate with curable polyimide, binding laminated sheets with heat, pressure HITACHI, LTD. (JP) 1985-07-02 US claimed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 US claimed
US-4393188-A PRINTED CIRCUITS HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-07-12 US claimed
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 US claimed
US-4283522-A BY HEATING WITH A DIAMINE HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-08-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049190-A1 HEAT-RESISTANT LIQUID CRYSTAL POLYMER FILM PUF60, HEATR6, CDH1 PRSS1 4075/4885F2 840/4885PRSS2 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.