SCHEMBL2231053

SCHEMBL2231053

CCCC([C]=O)N(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2232189 0.85 DNM1 (0.33)
SCHEMBL2234480 0.78
SCHEMBL7678871 0.77 FDPS (0.36)
SCHEMBL7675546 0.75
SCHEMBL7677389 0.75 FDPS (0.41)
SCHEMBL27574488 0.74
SCHEMBL7672462 0.73
SCHEMBL534991 0.72 GABRP (0.41)
SCHEMBL7675416 0.72
SCHEMBL15529854 0.72 CHRM2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US claimed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP claimed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO claimed
US-20140128399-A1 METHODS AND COMPOSITIONS FOR TREATING URINARY TRACT INFECTIONS USING AGENTS THAT MIMIC OR ELEVATE CYCLIC AMP DUKE UNIVERSITY (US) 2014-05-08 US disclosed
US-20110171195-A1 METHODS AND COMPOSITIONS FOR TREATING URINARY TRACT INFECTIONS USING AGENTS THAT MIMIC OR ELEVATE CYCLIC AMP DUKE UNIVERSITY (US) 2011-07-14 US disclosed
WO-2008157205-A2 METHODS AND COMPOSITIONS FOR TREATING URINARY TRACT INFECTIONS USING AGENTS THAT MIMIC OR ELEVATE CYCLIC AMP DUKE UNIVERSITY (US) 2008-12-24 WO disclosed
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US disclosed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP disclosed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO disclosed
US-5789439-A SKIN ULCERS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-08-04 US disclosed
EP-0448029-B1 Novel pharmaceutical uses of forskolin derivatives NIPPON KAYAKU KK (JP) 1995-12-20 EP disclosed
EP-0650723-A2 Novel pharmaceutical use of forskolin derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1995-05-03 EP disclosed
EP-0448029-A2 Novel pharmaceutical uses of forskolin derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-09-25 EP disclosed
US-4439433-A CEPHALOSPORIN ANTIBIOTICS ROUSSEL UCLAF (FR) 1984-03-27 US disclosed