Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malic Acid SCHEMBL29249135 | 0.95 | SMN1; SMN2 (0.48) | PRKCAPRKCDSMN1; SMN2GPR84CYP1A2 | |
| SCHEMBL25182618 | 0.88 | GPR84 (0.50) | PRKCAPRKCDGPR84CYP1A2MAPK1 | |
| SCHEMBL1242013 | 0.86 | GPR84 (0.43) | SMN1; SMN2GPR84CYP1A2MAPK1MEN1 | |
| SCHEMBL29924052 | 0.85 | PRKCA (0.44) | PRKCAPRKCDGPR84CHRM1AKR1A1 | |
| SCHEMBL25275003 | 0.85 | PRKCA (0.44) | PRKCAPRKCDGPR84CHRM1AKR1A1 | |
| SCHEMBL20398341 | 0.82 | PRKCA (0.40) | PRKCAPRKCDGPR84CYP1A2CHRM1 | |
| SCHEMBL29249145 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2GPR84CHRM1AKR1A1CHRM3 | |
| SCHEMBL2229574 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2GPR84LMNAMAPTTSHR | |
| SCHEMBL9784116 | 0.79 | GPR84 (0.56) | GPR84CYP1A2MAPK1MEN1GMNN | |
| SCHEMBL23361766 | 0.79 | GPR84 (0.56) | GPR84CYP1A2MAPK1MEN1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111201321-B | Genetically modified isopropyl malate isomerase enzyme complex and preparation of elongated 2-keto acids and C using same5-C10Method for preparing compounds | 陶氏环球技术有限责任公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-2343341-B1 | POLYORGANOSILOXANE COMPOSITION AND CURED PRODUCT THEREOF | UNIV MIE (JP) | 2014-08-27 | — | — | EP | disclosed |
| EP-2636692-A1 | CURABLE URETHANE COMPOSITION, CURED PRODUCT THEREOF, KIT AND CURRED PRODUCT PRODUCTION METHOD | Mie University (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-8455593-B2 | Polyorganosiloxane composition and cured production thereof | MIE UNIVERSITY (JP) | 2013-06-04 | — | — | US | disclosed |
| US-20110207864-A1 | POLYORGANOSILOXANE COMPOSITION AND CURED PRODUCTION THEREOF | MIE UNIVERSITY (JP) | 2011-08-25 | — | — | US | disclosed |
| EP-2343341-A1 | POLYORGANOSILOXANE COMPOSITION AND CURED PRODUCT THEREOF | Mie University (JP) | 2011-07-13 | — | — | EP | disclosed |