Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 4/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18627688 | 0.93 | KIF11 (0.47) | DHODHRXRARXRBPTGESALOX5 | |
| SCHEMBL13367484 | 0.93 | KIF11 (0.47) | DHODHRXRARXRBPTGESALOX5 | |
| SCHEMBL23381503 | 0.92 | CHKA (0.43) | DHODHRXRARXRBASIC1PTGES | |
| SCHEMBL22793707 | 0.87 | DHODH (0.57) | DHODHRXRARXRBASIC1KIF11 | |
| SCHEMBL6723846 | 0.87 | CHKA (0.49) | ALOX5HSD17B2CHKAMEN1KMT2A | |
| SCHEMBL6723962 | 0.87 | CHKA (0.49) | ALOX5HSD17B2CHKAMEN1KMT2A | |
| SCHEMBL6723803 | 0.87 | CHKA (0.49) | ALOX5HSD17B2CHKAMEN1KMT2A | |
| SCHEMBL6723412 | 0.85 | CHKA (0.51) | ALOX5HSD17B2CHKAMEN1KMT2A | |
| SCHEMBL24145271 | 0.85 | KIF11 (0.52) | PTGESALOX5KIF11RAB9A | |
| SCHEMBL22312869 | 0.85 | RXRA (0.47) | RXRARXRBPTGESALOX5KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020159279-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | 주식회사 엘지화학 | 2020-08-06 | — | — | WO | disclosed |