SCHEMBL13367484

SCHEMBL13367484

CN(c1ccc(-c2ccccc2)cc1)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.47
PTGES O14684 1/20 0.47
ALOX5 P09917 1/20 0.47
MEN1 O00255 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP19A1 P11511 2/20 0.42
CHKA P35790 1/20 0.41
TAAR1 Q96RJ0 1/20 0.39
HSD17B2 P37059 1/20 0.39
DHODH Q02127 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38
TP53 P04637 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18627688 1.00 KIF11 (0.47) KIF11PTGESALOX5MEN1RAB9A
SCHEMBL22312907 0.93 DHODH (0.48) KIF11PTGESALOX5MEN1RAB9A
SCHEMBL24145271 0.92 KIF11 (0.52) KIF11PTGESALOX5RAB9ATSHR
SCHEMBL5294134 0.90 MEN1 (0.50) PTGESALOX5MEN1RAB9AKMT2A
SCHEMBL23381503 0.88 CHKA (0.43) KIF11PTGESALOX5MEN1RAB9A
SCHEMBL20650056 0.86 KIF11 (0.46) KIF11PTGESALOX5MEN1RAB9A
SCHEMBL16344297 0.86 KIF11 (0.48) KIF11PTGESALOX5MEN1RAB9A
SCHEMBL14447688 0.86 KIF11 (0.48) KIF11PTGESALOX5MEN1RAB9A
SCHEMBL17849332 0.86 KIF11 (0.48) KIF11PTGESALOX5MEN1RAB9A
SCHEMBL18372419 0.86 KIF11 (0.48) KIF11PTGESALOX5MEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11584753-B2 Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) MERCK PATENT GMBH (DE) 2023-02-21 US disclosed
US-20210151690-A1 HOLE TRANSPORTING MATERIAL, METHOD OF MANUFACTURING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-05-20 US disclosed
EP-3544984-B1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
US-20190315764-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2019-10-17 US disclosed
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2019-05-23 US disclosed
WO-2018095888-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2018-05-31 WO disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 KIF11 3028/4885PTGES 1308/4885ALOX5 695/4885
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ETV6, ESR1 KIF11 1480/4885PTGES 2185/4885ALOX5 2172/4885
US-20210151690-A1 HOLE TRANSPORTING MATERIAL, METHOD OF MANUFACTURING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE SLC43A1, SLCO2A1, SLC7A5 KIF11 716/4885PTGES 1432/4885ALOX5 732/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 KIF11 3028/4885PTGES 1308/4885ALOX5 695/4885
US-20190315764-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) OCIAD1, OCIAD2, AOC1 KIF11 1925/4885PTGES 2929/4885ALOX5 514/4885
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 KIF11 1027/4885PTGES 3798/4885ALOX5 288/4885
US-11584753-B2 Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) OCIAD1, OCIAD2, AOC1 KIF11 1925/4885PTGES 2929/4885ALOX5 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.