Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | FGB | P02675 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22317843 | 0.81 | NOTUM (0.37) | NOTUMKDM4EGAAMAPTADRB1 | |
| SCHEMBL8593458 | 0.79 | L3MBTL1 (0.46) | NOTUMFGBL3MBTL1 | |
| SCHEMBL22717412 | 0.77 | NOTUM (0.39) | NOTUMGRM5CYP11B1CYP11B2ADRB1 | |
| SCHEMBL3595427 | 0.77 | HTR6 (0.51) | NOTUMGRM5CYP11B1CYP11B2GAA | |
| SCHEMBL27259961 | 0.77 | NOTUM (0.60) | NOTUMGAAFGBL3MBTL1NPC1 | |
| SCHEMBL23384700 | 0.77 | NOTUM (0.39) | NOTUMGRM5CYP11B1CYP11B2ADRB1 | |
| SCHEMBL27358451 | 0.77 | NPC1 (0.45) | NOTUMGRM5CYP11B1CYP11B2KDM4E | |
| SCHEMBL1082973 | 0.76 | NOTUM (0.41) | NOTUMGRM5CYP11B1CYP11B2ADRB1 | |
| SCHEMBL13545368 | 0.75 | TP53 (0.38) | NOTUMGRM5CYP11B1CYP11B2PIM1 | |
| SCHEMBL24184925 | 0.75 | NOTUM (0.37) | NOTUMGRM5CYP11B1CYP11B2FGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160175-A1 | QUINDOLINE COMPOUNDS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2020-08-06 | — | — | WO | disclosed |