Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FGB | P02675 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593458 | 0.84 | L3MBTL1 (0.46) | PIK3CDNOTUMFGBL3MBTL1 | |
| SCHEMBL27259961 | 0.79 | NOTUM (0.60) | NPC1PKMPKLRRAB9AHTR6 | |
| SCHEMBL22717412 | 0.79 | NOTUM (0.39) | NPC1PKMPKLRRAB9AHTR6 | |
| SCHEMBL23384700 | 0.79 | NOTUM (0.39) | NPC1PKMPKLRRAB9AHTR6 | |
| SCHEMBL3595427 | 0.79 | HTR6 (0.51) | HTR6NOTUMFGBL3MBTL1GRM5 | |
| SCHEMBL27259965 | 0.79 | CSF1R (0.38) | NPC1PKMPKLRRAB9AHTR6 | |
| SCHEMBL13180251 | 0.78 | PIK3CB (0.40) | HTR6PIK3CDPIK3CBPIK3CGNOTUM | |
| SCHEMBL13145758 | 0.78 | HTR6 (0.42) | NPC1PKMPKLRRAB9AHTR6 | |
| SCHEMBL29674819 | 0.78 | CDK6 (0.41) | HTR6PIK3CDPIK3CBPIK3CGCSF1R | |
| SCHEMBL17384723 | 0.77 | ALDH1A1 (0.36) | NPC1PKMPKLRRAB9AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130344-A1 | TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS | UNIQUEST PTY LIMITED (AU) | 2024-06-27 | — | — | WO | disclosed |