Styrene

Styrene

SCHEMBL2231382

C=CC(=O)N(c1ccccc1)c1ccccc1.C=Cc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 6/20 0.58
ALDH1A1 P00352 3/20 0.52
TSHR P16473 1/20 0.52
NPSR1 Q6W5P4 2/20 0.47
NPC1 O15118 1/20 0.40
POLB P06746 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
AKT1 P31749 1/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
AKR1C3 P42330 1/20 0.37
AKR1C1 Q04828 1/20 0.36
TGM2 P21980 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1629579 0.90 TRPM8 (0.57) TRPM8ALDH1A1NPSR1NPC1POLB
SCHEMBL28200399 0.80 ALDH1A1 (0.48) TRPM8ALDH1A1NPSR1NPC1POLB
SCHEMBL22196912 0.80 TRPM8 (0.47) TRPM8ALDH1A1NPSR1NPC1POLB
SCHEMBL25797681 0.80 TRPM8 (0.47) TRPM8ALDH1A1NPSR1NPC1POLB
SCHEMBL28449476 0.80 TRPM8 (0.47) TRPM8ALDH1A1NPSR1NPC1POLB
SCHEMBL18763031 0.80 TRPM8 (0.47) TRPM8ALDH1A1NPSR1NPC1POLB
Styrene SCHEMBL9330105 0.79 ALDH1A1 (0.54) TRPM8ALDH1A1TSHRNPC1RAB9A
Styrene SCHEMBL9330110 0.79 ALDH1A1 (0.54) TRPM8ALDH1A1TSHRNPC1RAB9A
Styrene SCHEMBL60237 0.78 ALDH1A1 (0.70) ALDH1A1TSHRKMT2AAKT1TDP1
Styrene SCHEMBL11061627 0.78 ALDH1A1 (0.70) ALDH1A1TSHRKMT2AAKT1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3103850-B1 VISCOSITY REGULATOR COMPOSITION ADEKA CORP (JP) 2018-06-06 EP disclosed
US-9982149-B2 Viscosity modifier composition ADEKA CORPORATION (JP) 2018-05-29 US disclosed
US-20170174908-A1 VISCOSITY MODIFIER COMPOSITION ADEKA CORPORATION (JP) 2017-06-22 US disclosed
US-9637563-B2 Surfactant composition DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2017-05-02 US disclosed
EP-3103850-A1 VISCOSITY REGULATOR COMPOSITION Adeka Corporation (JP) 2016-12-14 EP disclosed
US-20160137755-A1 SURFACTANT COMPOSITION DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2016-05-19 US disclosed
US-7981956-B2 Emulsion composition ADEKA CORPORATION (JP) 2011-07-19 US disclosed
EP-1693417-B1 Emulsion composition ADEKA CORP (JP) 2008-04-09 EP disclosed
US-20060189734-A1 Emulsion composition ADEKA CORPORATION (JP) 2006-08-24 US disclosed
EP-1693417-A1 Emulsion composition Asahi Denka Co., Ltd. (JP) 2006-08-23 EP disclosed
EP-0825167-B1 COMPOUNDS AND SURFACTANTS ASAHI DENKA KOGYO KK (JP) 2001-10-04 EP disclosed
US-5929290-A A HYDROPHILIC POLYETHER HAVING A FLUORO-SUBSTITUTED ALKYL END GROUP AND A (METH)ALLYL GLYCIDYL END GROUP; EMULSIFIERS AND DISPERSANTS FOR EMULSION AND SUSPENSION POLYMERIZATION, RESP.; RESIN REFORMING AGENTS; ANTISOILANTS FOR POLYESTERS ASAHI DENKA KOGYO K. K. (JP) 1999-07-27 US disclosed
EP-0825167-A1 COMPOUNDS AND SURFACTANTS ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1998-02-25 EP disclosed