Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380208 | 0.81 | LMNA (0.50) | LMNAPARP1KDM4EMAPK1HTT | |
| SCHEMBL25390691 | 0.79 | CYP1A2 (0.43) | LMNAKDM4EHTTTNFALDH1A1 | |
| SCHEMBL5706839 | 0.78 | CYP17A1 (0.44) | LMNAKDM4EMAPK1HTR1AADRA1D | |
| SCHEMBL5046238 | 0.76 | ALDH1A1 (0.47) | LMNAPARP1KDM4EMAPK1HTT | |
| SCHEMBL5042933 | 0.75 | PKM (0.42) | LMNAPARP1KDM4EMAPK1HTR1A | |
| SCHEMBL24010609 | 0.75 | CHRM4 (0.45) | LMNAPARP1TNFPKM | |
| SCHEMBL20247529 | 0.74 | PARP1 (0.43) | LMNAPARP1KDM4EMAPK1HTT | |
| SCHEMBL10670438 | 0.73 | PKM (0.47) | LMNAPARP1KDM4EMAPK1HTT | |
| SCHEMBL7498304 | 0.73 | ALDH1A1 (0.48) | LMNAKDM4EMAPK1HTTPKM | |
| SCHEMBL862347 | 0.73 | CCR1 (0.48) | LMNAPARP1KDM4EMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156512-A1 | AROMATIC (HETERO)CYCLIC ETHER COMPOUND HAVING INSECTICIDAL ACTIVITY, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 华东理工大学 | 2020-08-06 | — | — | WO | disclosed |