SCHEMBL2231675

SCHEMBL2231675

CCCC1C2=C(CCCC2)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.35
ADRA2C P18825 1/20 0.35
PTGS2 P35354 1/20 0.35
HTR3A P46098 1/20 0.35
PDE4D Q08499 1/20 0.35
HTR2A P28223 2/20 0.35
BCHE P06276 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
ACHE P22303 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2234349 0.87 HTR2A (0.37) HRH1ADRA2CPTGS2HTR3APDE4D
SCHEMBL3824349 0.81 ADRA2C (0.35) HRH1ADRA2CPTGS2HTR3APDE4D
SCHEMBL1996543 0.74 HTR2A (0.54) HRH1ADRA2CHTR2ABCHECYP1A2
SCHEMBL2231523 0.74 ADRA2C (0.40) HRH1ADRA2CPTGS2HTR3APDE4D
SCHEMBL2232629 0.72 ADRA2C (0.37) HRH1ADRA2CPTGS2HTR3APDE4D
SCHEMBL6251581 0.70 ADRA2C (0.36) HRH1ADRA2CPTGS2HTR3APDE4D
SCHEMBL9250186 0.70 ALDH1A1 (0.39) HRH1ADRA2CPTGS2HTR3APDE4D
SCHEMBL22879574 0.70 ADRA2C (0.40) HRH1ADRA2CPTGS2HTR3APDE4D
SCHEMBL2231794 0.70 ADRA2C (0.37) HRH1ADRA2CPTGS2HTR3APDE4D
SCHEMBL6251445 0.70 ADRA2C (0.37) HRH1ADRA2CPTGS2HTR3APDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461270-B2 Olefin/aromatic vinyl copolymer, process for production thereof, resin compositions containing the copolymer, and stretched products of the copolymer IDEMITSU KOSAN CO., LTD. (JP) 2013-06-11 US disclosed
EP-2157108-B1 OLEFIN/AROMATIC VINYL COPOLYMER, PROCESS FOR PRODUCTION THEREOF, RESIN COMPOSITIONS CONTAINING THE COPOLYMER, AND STRETCHED PRODUCTS OF THE COPOLYMER IDEMITSU KOSAN CO (JP) 2013-02-20 EP disclosed
US-20110172366-A1 OLEFIN/AROMATIC VINYL COPOLYMER, PROCESS FOR PRODUCTION THEREOF, RESIN COMPOSITIONS CONTAINING THE COPOLYMER, AND STRETCHED PRODUCTS OF THE COPOLYMER IDEMITSU KOSAN CO., LTD. (JP) 2011-07-14 US disclosed
EP-2157108-A1 OLEFIN/AROMATIC VINYL COPOLYMER, PROCESS FOR PRODUCTION THEREOF, RESIN COMPOSITIONS CONTAINING THE COPOLYMER, AND STRETCHED PRODUCTS OF THE COPOLYMER Idemitsu Kosan Co., Ltd. (JP) 2010-02-24 EP disclosed