Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 11/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.37 |
| ▸ | PTGES | O14684 | 6/20 | 0.37 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231793 | 0.86 | PPARG (0.48) | PPARGPSEN1ALOX5PTGES | |
| SCHEMBL2235842 | 0.84 | TDP1 (0.37) | PPARGALKBH1PSEN1ALOX5PTGES | |
| SCHEMBL2233200 | 0.84 | ALOX5 (0.35) | PPARGALOX5ACACBMRGPRX4ACACA | |
| SCHEMBL2232578 | 0.83 | PDPK1 (0.34) | MRGPRX4 | |
| SCHEMBL13581943 | 0.81 | ALKBH1 (0.40) | ALKBH1ACACBMRGPRX4ACACA | |
| SCHEMBL13581942 | 0.81 | ALKBH1 (0.40) | ALKBH1ACACBMRGPRX4ACACA | |
| SCHEMBL2231788 | 0.80 | APP (0.38) | PPARGALKBH1PTGESACACB | |
| SCHEMBL2234688 | 0.78 | MAOB (0.41) | ACACBMRGPRX4ACACA | |
| SCHEMBL2234682 | 0.78 | MAOB (0.41) | ACACBMRGPRX4ACACA | |
| SCHEMBL2234686 | 0.78 | MAOB (0.41) | ACACBMRGPRX4ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |