Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231831 | 0.85 | KMT2A (0.41) | MAOBALKBH1MEN1KMT2AGCK | |
| SCHEMBL2231791 | 0.84 | PPARG (0.40) | ALKBH1PPARGPTGESALOX5PSEN1 | |
| SCHEMBL2235847 | 0.84 | ALOX5 (0.41) | PPARGPOLBMAPTMAPK1PTGES | |
| SCHEMBL2232578 | 0.83 | PDPK1 (0.34) | MEN1KMT2APOLB | |
| SCHEMBL13582347 | 0.80 | PTPN1 (0.43) | MAOBMEN1KMT2APTPN1POLB | |
| SCHEMBL13582345 | 0.80 | PTPN1 (0.43) | MAOBMEN1KMT2APTPN1POLB | |
| SCHEMBL13582548 | 0.79 | MAOB (0.45) | MAOBALKBH1MEN1KMT2AGCK | |
| SCHEMBL13582543 | 0.79 | MAOB (0.45) | MAOBALKBH1MEN1KMT2AGCK | |
| SCHEMBL13582546 | 0.79 | MAOB (0.45) | MAOBALKBH1MEN1KMT2AGCK | |
| SCHEMBL2235837 | 0.78 | ALOX5 (0.42) | TDP1MAOBMEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |