Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170531 | 0.79 | RAB9A (0.64) | RAB9ANPC1POLBLMNAKDM4E | |
| SCHEMBL5756863 | 0.79 | ITK (0.58) | RAB9ANPC1POLBLMNAKDM4E | |
| SCHEMBL6170526 | 0.77 | RAB9A (0.67) | RAB9ANPC1POLBLMNAKDM4E | |
| SCHEMBL5408163 | 0.76 | NPC1 (0.60) | RAB9ANPC1POLBLMNAKDM4E | |
| SCHEMBL10132645 | 0.75 | KDM4E (0.57) | RAB9ANPC1POLBLMNAKDM4E | |
| SCHEMBL13373392 | 0.75 | RAB9A (0.61) | RAB9ANPC1POLBLMNAKDM4E | |
| SCHEMBL13947279 | 0.75 | KDM4E (0.79) | RAB9ANPC1POLBLMNAKDM4E | |
| SCHEMBL166484 | 0.74 | LMNA (0.82) | RAB9ANPC1POLBLMNAKDM4E | |
| SCHEMBL3202800 | 0.74 | RAB9A (0.57) | RAB9ANPC1POLBLMNAKDM4E | |
| SCHEMBL14025813 | 0.74 | SLC40A1 (0.66) | RAB9ANPC1POLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345642-A1 | Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents | POLICHEM S.A. (LU) | 2011-07-20 | — | — | EP | claimed |