Methane

Methane

SCHEMBL22319781

C.CC1CCC2C(C)CCC(C(C)C)C2C1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 4/20 0.48
TRPA1 O75762 2/20 0.48
EPHX1 P07099 3/20 0.42
ALDH1A1 P00352 2/20 0.37
KCNA5 P22460 1/20 0.35
TRPV1 Q8NER1 3/20 0.32
LMNA P02545 2/20 0.32
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29449737 0.98 TRPM8 (0.50) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL25349880 0.98 TRPM8 (0.50) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL9080881 0.87 TRPM8 (0.60) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL27969261 0.78 TRPA1 (0.47) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL29444900 0.78 TRPM8 (0.39) TRPM8TRPA1EPHX1ALDH1A1
SCHEMBL8548065 0.77 TRPM8 (0.59) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL27969212 0.74 TRPA1 (0.47) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL7101233 0.74 TRPA1 (0.40) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL9487930 0.73 TRPM8 (0.55) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL9340641 0.73 TRPM8 (0.55) TRPM8TRPA1EPHX1ALDH1A1KCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240293356-A1 Cannabinoid Formulations ENDOCANNA HEALTH INC (US) 2024-09-05 US disclosed
US-11857530-B2 Cannabinoid formulations ENDOCANNA HEALTH, INC. (US) 2024-01-02 US disclosed
EP-3703672-A1 CANNABINOID FORMULATIONS Endocanna Health, Inc. (US) 2020-09-09 EP disclosed
US-20200253921-A1 Cannabinoid Formulations ENDOCANNA HEALTH, INC. 2020-08-13 US disclosed