SCHEMBL22320291

SCHEMBL22320291

COCOc1ccc(C)cc1-c1ccccc1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 9/20 0.47
MAPT P10636 6/20 0.47
HPGD P15428 5/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP2C9 P11712 1/20 0.47
TDP1 Q9NUW8 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.41
ALDH1A1 P00352 3/20 0.40
MAOB P27338 2/20 0.40
MAPK1 P28482 2/20 0.40
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MAOA P21397 1/20 0.39
SYK P43405 1/20 0.38
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23092046 0.84 KCNN4 (0.43) L3MBTL1MAPTHPGDNPC1RAB9A
SCHEMBL30930957 0.80 L3MBTL1 (0.42) L3MBTL1MAPTHPGDNPC1RAB9A
SCHEMBL22320321 0.79 PTGDR2 (0.40) L3MBTL1HPGDNPC1CYP1A2CYP2C19
SCHEMBL2703926 0.79 L3MBTL1 (0.58) L3MBTL1MAPTHPGDNPC1RAB9A
SCHEMBL30423350 0.79 L3MBTL1 (0.58) L3MBTL1MAPTHPGDNPC1RAB9A
SCHEMBL15451042 0.75 L3MBTL1 (0.47) L3MBTL1MAPTHPGDNPC1RAB9A
SCHEMBL14460781 0.74 PTGDR2 (0.40) L3MBTL1MAPTHPGDNPC1RAB9A
SCHEMBL22320292 0.73 PTGDR2 (0.35) L3MBTL1MAPTHPGDNPC1RAB9A
SCHEMBL14125147 0.73 PTGDR2 (0.42) L3MBTL1MAPTHPGDCYP2C19CYP2C9
SCHEMBL30306134 0.73 PTGDR2 (0.38) L3MBTL1MAPTHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3924395-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF ExxonMobil Chemical Patents Inc. (US) 2021-12-22 EP disclosed
US-11203654-B2 Bis(aryl phenolate) lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-21 US disclosed
US-11203654-B2 Bis(aryl phenolate) lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-21 US disclosed
WO-2020167824-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
WO-2020167824-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
US-20200254431-A1 BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed
US-20200254431-A1 BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11203654-B2 Bis(aryl phenolate) lewis base catalysts and methods thereof PHKB, TYR, ELL L3MBTL1 3000/4885MAPT 2984/4885HPGD 1701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.