SCHEMBL22320292

SCHEMBL22320292

COCOc1ccc(C)cc1-c1ccccc1B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
SYK P43405 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MDM2 Q00987 1/20 0.33
KCNN4 O15554 1/20 0.31
HPGD P15428 3/20 0.31
L3MBTL1 Q9Y468 3/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
NPC1 O15118 2/20 0.30
MAPT P10636 2/20 0.30
RAB9A P51151 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
LPL P06858 1/20 0.30
LIPG Q9Y5X9 1/20 0.30
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23092057 0.87 KCNN4 (0.37) ALDH1A1KCNN4HPGDMAPTLPL
SCHEMBL22320285 0.83 ACHE (0.33) ALDH1A1HPGDL3MBTL1MAPK1MAPT
SCHEMBL28625046 0.81 KDM4E (0.33) PTGDR2SMN1; SMN2KDM4EALDH1A1LMNA
SCHEMBL19087000 0.80 CSF1R (0.34) ALDH1A1HPGDL3MBTL1MAPK1MAPT
SCHEMBL4259193 0.79 LPL (0.38) LPLLIPGEGFR
SCHEMBL29605546 0.79 LPL (0.38) LPLLIPGEGFR
SCHEMBL22320306 0.78
SCHEMBL22320153 0.78 CYP3A4 (0.30)
SCHEMBL22320317 0.78
SCHEMBL28906404 0.76 MRGPRX4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3924395-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF ExxonMobil Chemical Patents Inc. (US) 2021-12-22 EP disclosed
US-11203654-B2 Bis(aryl phenolate) lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-21 US disclosed
US-11203654-B2 Bis(aryl phenolate) lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-21 US disclosed
CN-113423742-A Bis (arylphenolate) lewis base catalysts and processes thereof 埃克森美孚化学专利公司 2021-09-21 CN disclosed
WO-2020167824-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
WO-2020167824-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
US-20200254431-A1 BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed
US-20200254431-A1 BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11203654-B2 Bis(aryl phenolate) lewis base catalysts and methods thereof PHKB, TYR, ELL PTGDR2 1682/4885SMN1; SMN2 3843/4885SYK 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.