Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.59 |
| ▸ | CCNK | O75909 | 1/20 | 0.52 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 4/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.49 |
| ▸ | CDK2 | P24941 | 4/20 | 0.49 |
| ▸ | PIM1 | P11309 | 3/20 | 0.49 |
| ▸ | PRKACA | P17612 | 3/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | CHUK | O15111 | 2/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 2/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.49 |
| ▸ | PRKCG | P05129 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | MARK3 | P27448 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27818294 | 0.84 | CYP19A1 (0.60) | CYP19A1CCNKCDK12GSK3BFLT3 | |
| SCHEMBL16264766 | 0.82 | CCNK (0.46) | CYP19A1CCNKCDK12CDK2NPC1 | |
| SCHEMBL16263155 | 0.80 | CCNE1 (0.37) | CYP19A1CCNKCDK12CDK2MAPK1 | |
| SCHEMBL22510634 | 0.79 | CYP19A1 (0.82) | CYP19A1CCNKCDK12GSK3BFLT3 | |
| SCHEMBL18625817 | 0.79 | NAMPT (0.41) | CYP19A1CCNKCDK12CDK2NPC1 | |
| SCHEMBL20435497 | 0.77 | SRC (0.57) | CYP19A1GSK3BFLT3NPC1RAB9A | |
| SCHEMBL29275462 | 0.76 | CYP19A1 (0.66) | CYP19A1CCNKCDK12GSK3BFLT3 | |
| SCHEMBL27818284 | 0.75 | NR1I3 (0.50) | CYP19A1CCNKCDK12GSK3BROCK2 | |
| SCHEMBL935182 | 0.75 | CYP19A1 (1.00) | CYP19A1GSK3BFLT3ROCK2CDK2 | |
| SCHEMBL15836586 | 0.75 | CYP19A1 (0.93) | CYP19A1GSK3BFLT3ROCK2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11027260-B2 | Low pressure nanowire membrane for catalytic reactions and methods of making and using the same | UCHICAGO ARGONNE, LLC (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200254426-A1 | LOW PRESSURE NANOWIRE MEMBRANE FOR CATALYTIC REACTIONS AND METHODS OF MAKING AND USING THE SAME | UCHICAGO ARGONNE, LLC | 2020-08-13 | — | — | US | disclosed |