Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 14/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GRK6 | P43250 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199705 | 0.91 | EGLN1 (0.61) | EGLN1NPC1RAB9AGRK6ALDH1A1 | |
| SCHEMBL2201303 | 0.89 | EGLN1 (0.62) | EGLN1NAMPTALDH1A1 | |
| SCHEMBL2202067 | 0.76 | EGLN1 (0.63) | EGLN1ALDH1A1 | |
| SCHEMBL2202613 | 0.75 | EGLN1 (0.65) | EGLN1ALDH1A1 | |
| SCHEMBL15327083 | 0.74 | RAB9A (0.46) | NPC1RAB9AALDH1A1 | |
| SCHEMBL15327091 | 0.74 | NAMPT (0.46) | EGLN1NPC1RAB9ANAMPTALDH1A1 | |
| SCHEMBL2203862 | 0.72 | EGLN1 (0.74) | EGLN1NPC1RAB9AALDH1A1 | |
| SCHEMBL2201945 | 0.72 | EGLN1 (0.66) | EGLN1ALDH1A1 | |
| SCHEMBL7685030 | 0.70 | EGLN1 (0.74) | EGLN1ALDH1A1 | |
| SCHEMBL7691436 | 0.69 | EGLN1 (0.70) | EGLN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519503-A1 | SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES FOR USE AS ANTIFUNGAL AGENTS | POLICHEM S.A. (LU) | 2012-11-07 | — | — | EP | claimed |
| WO-2011080265-A1 | SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES FOR USE AS ANTIFUNGAL AGENTS | POLICHEM S.A. (LU) | 2011-07-07 | — | — | WO | claimed |