Penicillamine

Penicillamine

SCHEMBL3138111

CC(C)(S)[C@@H](N)C(=O)O.[NaH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.95
PTGS1 P23219 2/20 0.95
MAPT P10636 2/20 0.95
SLC7A5 Q01650 2/20 0.36
SLC7A11 Q9UPY5 1/20 0.35
GRIK1 P39086 1/20 0.32
ENPEP Q07075 3/20 0.32
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
HPGD P15428 2/20 0.30
HSD17B10 Q99714 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
ABCB11 O95342 1/20 0.30
F2 P00734 1/20 0.30
TP53 P04637 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Penicillamine SCHEMBL3643254 1.00 ALDH1A1 (0.95) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL129296 0.97 ALDH1A1 (1.00) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL4343 0.97
Dl-Penicillamine SCHEMBL22322162 0.97 ALDH1A1 (1.00) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL603349 0.97 ALDH1A1 (1.00) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Dl-Penicillamine SCHEMBL57527 0.97
Dl-Penicillamine SCHEMBL159653 0.97 ALDH1A1 (1.00) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Dl-Penicillamine SCHEMBL4344 0.97
Penicillamine SCHEMBL10789333 0.95 ALDH1A1 (0.95) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Dl-Penicillamine SCHEMBL7932150 0.95 ALDH1A1 (0.95) ALDH1A1PTGS1MAPTSLC7A5SLC7A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2203192-A1 WOUND CARE FORMULATION Northern Health And Social Care Trust (GB) 2010-07-07 EP disclosed
WO-2009037500-A1 WOUND CARE FORMULATION NORTHERN HEALTH AND SOCIAL CARE TRUST (GB) 2009-03-26 WO disclosed
US-20080113011-A1 Compositions and methods for enhanced mucosal delivery of interferon beta NASTECH PHARMACEUTICAL COMPANY INC. (US) 2008-05-15 US disclosed
EP-1539220-A4 COMPOSITIONS AND METHODS FOR ENHANCED MUCOSAL DELIVERY OF INTERFERON BETA NASTECH PHARM CO (US) 2008-04-02 EP disclosed
EP-1539220-A2 COMPOSITIONS AND METHOD FOR ENHANCED MUCOSAL DELIVERY OF INTERFERON BETA Nastech Pharmaceutical Company Inc. (US) 2005-06-15 EP disclosed
WO-2004002404-A2 COMPOSITIONS AND METHOD FOR ENHANCED MUCOSAL DELIVERY OF INTERFERON BETA NASTECH PHARMACEUTICAL COMPANY INC. (US) 2004-01-08 WO disclosed