Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30109018 | 0.78 | CYP2A6 (0.53) | — | |
| SCHEMBL22322323 | 0.76 | KDR (0.44) | PRMT5WDR77PDE10A | |
| SCHEMBL22322302 | 0.75 | RORC (0.38) | — | |
| SCHEMBL22322311 | 0.74 | AOC3 (0.47) | PIK3C3AOC3PRMT5WDR77PDE10A | |
| SCHEMBL23346568 | 0.74 | PIK3C3 (0.46) | PIK3C3PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL10841843 | 0.74 | CREBBP (0.47) | AOC3 | |
| SCHEMBL16680645 | 0.73 | PIK3CD (0.46) | PIK3C3PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL28113781 | 0.73 | PIK3CD (0.52) | PIK3C3PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL30630189 | 0.73 | PIK3CD (0.46) | PIK3C3PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL22322322 | 0.72 | PDE10A (0.38) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161270-A1 | HERBICIDAL PYRIDAZINUM BASED COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020161270-A1 | HERBICIDAL PYRIDAZINUM BASED COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |