Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22322323 | 0.78 | KDR (0.44) | PDE10APRMT5WDR77KDR | |
| SCHEMBL22322302 | 0.74 | RORC (0.38) | — | |
| SCHEMBL22322332 | 0.72 | PIK3C3 (0.48) | PDE10APRMT5WDR77PIK3CDPIK3CA | |
| SCHEMBL1773633 | 0.71 | KIF11 (0.42) | PDE10AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL22338331 | 0.70 | HDAC6 (0.34) | PDE10AMEN1POLBKMT2AKDM4E | |
| SCHEMBL22322351 | 0.68 | CSNK2A1 (0.34) | PDE10AMEN1POLBKMT2AKDM4E | |
| SCHEMBL22322311 | 0.68 | AOC3 (0.47) | PDE10APRMT5WDR77USP30 | |
| SCHEMBL12095027 | 0.66 | BRD4 (0.34) | PDE10AMEN1POLBKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL25238458 | 0.65 | GAA (0.34) | PDE10AKMT2APKMADORA2A | |
| SCHEMBL10461993 | 0.65 | L3MBTL1 (0.41) | POLBKDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161270-A1 | HERBICIDAL PYRIDAZINUM BASED COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020161270-A1 | HERBICIDAL PYRIDAZINUM BASED COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |