Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.53 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12864319 | 0.78 | BRD4 (0.47) | CYP2C9CYP2C19ALDH1A1CYP3A4GLO1 | |
| SCHEMBL22322332 | 0.78 | PIK3C3 (0.48) | — | |
| SCHEMBL18654144 | 0.76 | KCNH2 (0.43) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL31743133 | 0.76 | GRM2 (0.71) | CYP11B1CYP11B2CYP1A2CYP17A1CYP19A1 | |
| SCHEMBL30557214 | 0.75 | HSD17B1 (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL30109067 | 0.75 | CREBBP (0.59) | CYP2A6CYP2E1CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL23187978 | 0.74 | CYP11B2 (0.64) | CYP2A6CYP2C19ALDH1A1CYP2A13CYP11B1 | |
| SCHEMBL18656033 | 0.74 | PIK3CD (0.43) | ALDH1A1BACE1 | |
| SCHEMBL23346568 | 0.72 | PIK3C3 (0.46) | — | |
| SCHEMBL16680645 | 0.72 | PIK3CD (0.46) | CYP2A6CYP2E1CYP2B6CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542275-B2 | Substituted imidazolidin-2-one derivatives as PRMT5 inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2023-01-03 | — | — | US | claimed |
| US-11542275-B2 | Substituted imidazolidin-2-one derivatives as PRMT5 inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542275-B2 | Substituted imidazolidin-2-one derivatives as PRMT5 inhibitors | PRMT5, PRMT1, PRMT8 | CYP2A6 4121/4885CYP2E1 1712/4885CYP2C9 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.