Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16872440 | 0.87 | ALOX5 (0.41) | ALOX5KDM4EALDH1A1PTGS2ADORA2A | |
| SCHEMBL16321041 | 0.84 | ALOX5 (0.39) | ALOX5KDM4EALDH1A1PTGS2ADORA2A | |
| SCHEMBL19742067 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1RAB9ASMN1; SMN2ADORA2A | |
| SCHEMBL1487708 | 0.80 | PTGS2 (0.45) | ALOX5KDM4EALDH1A1PTGS2ADORA2A | |
| Benzene SCHEMBL27761468 | 0.80 | PTGS2 (0.47) | ALOX5KDM4EALDH1A1PTGS2ADORA2A | |
| SCHEMBL7802382 | 0.80 | PTGS2 (0.47) | ALOX5KDM4EALDH1A1PTGS2ADORA2A | |
| SCHEMBL28641765 | 0.77 | PTGS2 (0.46) | ALOX5KDM4EALDH1A1PTGS2ADORA2A | |
| SCHEMBL21295467 | 0.77 | PTGS2 (0.49) | ALOX5KDM4EALDH1A1PTGS2ADORA2A | |
| SCHEMBL1487707 | 0.76 | ALOX5 (0.39) | ALOX5KDM4EALDH1A1ADORA2AADORA1 | |
| SCHEMBL28399939 | 0.76 | ALOX5 (0.42) | ALOX5KDM4EALDH1A1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356709-A1 | OPTOELECTRONIC DEVICES | Cambridge Enterprise Ltd. (GB) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010064028-A1 | OPTOELECTRONIC DEVICES | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-06-10 | — | — | WO | disclosed |