Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | BCHE | P06276 | 12/20 | 0.66 |
| ▸ | ACHE | P22303 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22147543 | 0.89 | LMNA (0.79) | LMNAMAPTHTTBCHEACHE | |
| SCHEMBL9009230 | 0.82 | LMNA (0.68) | LMNAMAPTHTTBCHEACHE | |
| SCHEMBL3455868 | 0.79 | ALDH1A1 (0.70) | LMNAMAPTHTTSMN1; SMN2HPGD | |
| SCHEMBL31061043 | 0.79 | BCHE (1.00) | LMNAMAPTBCHEACHETP53 | |
| SCHEMBL9009016 | 0.78 | LMNA (0.62) | LMNAMAPTHTTBCHEACHE | |
| SCHEMBL14732437 | 0.76 | BCHE (0.67) | LMNAMAPTHTTBCHEACHE | |
| SCHEMBL9009014 | 0.76 | LMNA (0.60) | LMNAMAPTHTTBCHEACHE | |
| SCHEMBL27593699 | 0.76 | BCHE (0.66) | LMNAMAPTHTTBCHEACHE | |
| SCHEMBL28621381 | 0.76 | BCHE (1.00) | BCHEACHEHPGD | |
| SCHEMBL30966338 | 0.75 | MAPT (1.00) | LMNAMAPTBCHEACHETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163236-A1 | TREATING LONG QT SYNDROME | THE GENERAL HOSPITAL CORPORATION (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020163236-A1 | TREATING LONG QT SYNDROME | THE GENERAL HOSPITAL CORPORATION (US) | 2020-08-13 | — | — | WO | disclosed |