SCHEMBL9009230

SCHEMBL9009230

COc1ccccc1C(=O)N1c2ccc(N(C)C)cc2Sc2cc(N(C)C)ccc21

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.68
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
MAPK1 P28482 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
MAPT P10636 2/20 0.51
HTT P42858 2/20 0.51
BCHE P06276 8/20 0.48
ACHE P22303 4/20 0.48
SNCA P37840 1/20 0.48
HPGD P15428 1/20 0.43
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009016 0.91 LMNA (0.62) LMNAMEN1KMT2AMAPK1TDP1
SCHEMBL9009060 0.84 MAPK1 (0.70) LMNAMEN1KMT2AMAPK1TDP1
SCHEMBL9009048 0.82 MAPK1 (0.68) LMNAMEN1KMT2AMAPK1TDP1
SCHEMBL9009014 0.82 LMNA (0.60) LMNAMEN1KMT2AMAPK1TDP1
SCHEMBL22323680 0.82 LMNA (1.00) LMNAMAPTHTTBCHEACHE
SCHEMBL8981610 0.81 MAPK1 (0.65) LMNAMEN1KMT2AMAPK1TDP1
SCHEMBL10602592 0.80 MAPK1 (0.64) LMNAMEN1KMT2AMAPK1TDP1
SCHEMBL29406737 0.79 MEN1 (1.00) MEN1KMT2AMAPK1TDP1L3MBTL1
SCHEMBL388483 0.79 MEN1 (1.00) MEN1KMT2AMAPK1TDP1L3MBTL1
SCHEMBL9009137 0.78 MEN1 (0.72) MEN1KMT2AMAPK1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565402-A RECORDING LAYER CONTAINING BLACK-FORMING FLUORAN DERIVATIVE AS BASIC DYE, PHENOTHIAZINE DERIVATIVE, DIPHENYL SULFONE DERIVATIVE COLOR ACCEPTOR NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed