Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.52 |
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4238030 | 0.86 | ESR1 (0.55) | ESR1ESR2ARVDRCYP2C19 | |
| SCHEMBL29690460 | 0.86 | ESR1 (0.55) | ESR1ESR2ARVDRCYP2C19 | |
| SCHEMBL7835864 | 0.85 | CYP2C19 (0.46) | ESR1ESR2CYP2C19HIF1ATDP1 | |
| SCHEMBL10411503 | 0.80 | CHEK1 (0.49) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL9774879 | 0.79 | ESR1 (0.45) | ESR1ESR2CYP2C19HIF1A | |
| SCHEMBL2232385 | 0.79 | ESR1 (0.53) | ESR1ESR2ARVDR | |
| SCHEMBL6535890 | 0.78 | SLC13A5 (0.44) | VDRCYP2C19 | |
| SCHEMBL7823625 | 0.77 | ALDH1A1 (0.46) | CYP2C19HIF1ATDP1 | |
| SCHEMBL29492899 | 0.77 | ESR1 (0.70) | ESR1ESR2ARVDRTP53 | |
| SCHEMBL5990790 | 0.77 | ESR1 (0.56) | ESR1ESR2ARCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689902-B2 | REDUCTIVE ALKYLATION | AJINOMOTO CO., INC. (JP) | 2004-02-10 | — | — | US | claimed |
| US-20030032842-A1 | Novel arylpropyl aldehyde derivatives, processes for producing the same, and methods of using the same | AJINOMOTO CO., INC. (JP) | 2003-02-13 | — | — | US | claimed |
| CN-1395551-A | Novel arylpropionaldehyde derivatives and production and use of the same | AJINOMOTO KK (JP) | 2003-02-05 | — | — | CN | claimed |
| EP-1249442-A1 | NOVEL ARYLPROPIONALDEHYDE DERIVATIVES AND PRODUCTION AND USE OF THE SAME | Ajinomoto Co., Inc. (JP) | 2002-10-16 | — | — | EP | claimed |
| EP-1249442-A4 | NOVEL ARYLPROPIONALDEHYDE DERIVATIVES AND PRODUCTION AND USE OF THE SAME | AJINOMOTO KK (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-6689902-B2 | REDUCTIVE ALKYLATION | AJINOMOTO CO., INC. (JP) | 2004-02-10 | — | — | US | disclosed |
| US-6689902-B2 | REDUCTIVE ALKYLATION | AJINOMOTO CO., INC. (JP) | 2004-02-10 | — | — | US | disclosed |
| US-20030032842-A1 | Novel arylpropyl aldehyde derivatives, processes for producing the same, and methods of using the same | AJINOMOTO CO., INC. (JP) | 2003-02-13 | — | — | US | disclosed |
| US-20030032842-A1 | Novel arylpropyl aldehyde derivatives, processes for producing the same, and methods of using the same | AJINOMOTO CO., INC. (JP) | 2003-02-13 | — | — | US | disclosed |
| CN-1395551-A | Novel arylpropionaldehyde derivatives and production and use of the same | AJINOMOTO KK (JP) | 2003-02-05 | — | — | CN | disclosed |
| CN-1395551-A | Novel arylpropionaldehyde derivatives and production and use of the same | AJINOMOTO KK (JP) | 2003-02-05 | — | — | CN | disclosed |
| EP-1249442-A1 | NOVEL ARYLPROPIONALDEHYDE DERIVATIVES AND PRODUCTION AND USE OF THE SAME | Ajinomoto Co., Inc. (JP) | 2002-10-16 | — | — | EP | disclosed |
| EP-1249442-A1 | NOVEL ARYLPROPIONALDEHYDE DERIVATIVES AND PRODUCTION AND USE OF THE SAME | Ajinomoto Co., Inc. (JP) | 2002-10-16 | — | — | EP | disclosed |
| WO-2001053243-A1 | NOVEL ARYLPROPIONALDEHYDE DERIVATIVES AND PRODUCTION AND USE OF THE SAME | AJINOMOTO CO., INC. (JP) | 2001-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032842-A1 | Novel arylpropyl aldehyde derivatives, processes for producing the same, and methods of using the same | ALDH7A1, ASPH, DDC | ESR1 4324/4885ESR2 4194/4885AR 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.