Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679689 | 0.79 | THRB (0.44) | ALDH1A1LMNAHSD17B10KMT2AALOX15 | |
| SCHEMBL27468276 | 0.78 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL2230421 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10KMT2AALOX15 | |
| SCHEMBL1936374 | 0.77 | HDAC6 (0.39) | ALDH1A1LMNAHSD17B10KMT2AGAA | |
| SCHEMBL10614784 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10KMT2AALOX15 | |
| SCHEMBL11528573 | 0.76 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9493220 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10KMT2AALOX15 | |
| SCHEMBL8773032 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10KMT2AALOX15 | |
| SCHEMBL27465345 | 0.76 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10KMT2ATSHR | |
| SCHEMBL10617663 | 0.75 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130156857-A1 | Pharmaceutical Compositions Containing Diacerein | TWI BIOTECHNOLOGY, INC. (TW) | 2013-06-20 | — | — | US | disclosed |
| EP-2349289-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING DIACEREIN | TWI Biotechnology, Inc. (TW) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010051296-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING DIACEREIN | ANCHEN LABORATORIES, INC. (US) | 2010-05-06 | — | — | WO | disclosed |
| US-20100104651-A1 | Pharmaceutical Compositions Containing Diacerein | TWI BIOTECHNOLOGY, INC. (TW) | 2010-04-29 | — | — | US | disclosed |
| US-20070014858-A1 | Method for controlling lag time of in-situ passageway formation in osmotic delivery system | EMPAX PHARMA INC. | 2007-01-18 | — | — | US | disclosed |