Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325872 | 0.91 | MAPT (0.44) | HSPB1MAPTPOLBTDP1MEN1 | |
| SCHEMBL22325973 | 0.83 | MEN1 (0.44) | HSPB1MAPTPOLBTDP1MEN1 | |
| SCHEMBL6349 | 0.82 | TDP1 (0.50) | HSPB1MAPTTDP1MEN1KMT2A | |
| SCHEMBL29512805 | 0.82 | TDP1 (0.50) | HSPB1MAPTTDP1MEN1KMT2A | |
| SCHEMBL11649655 | 0.80 | HSPB1 (0.50) | HSPB1MAPTPOLBTDP1MEN1 | |
| SCHEMBL31470001 | 0.77 | HSPB1 (0.61) | HSPB1MAPTPOLBTDP1MEN1 | |
| SCHEMBL22326019 | 0.76 | PIN1 (0.35) | HSPB1MAPTPOLBTDP1MEN1 | |
| SCHEMBL6295009 | 0.75 | MERTK (0.50) | HSPB1MAPTPOLBMEN1KMT2A | |
| SCHEMBL3032884 | 0.75 | TDP1 (0.46) | HSPB1CA12CA1CA2CA7 | |
| SCHEMBL10884667 | 0.74 | RECQL (0.51) | HSPB1MAPTPOLBTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |