Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325829 | 0.83 | RHEB (0.43) | MAPTKMT2AKEAP1BRD4RHEB | |
| SCHEMBL22325872 | 0.83 | MAPT (0.44) | PIN1MAPTPOLBALDH1A1MEN1 | |
| SCHEMBL22325973 | 0.79 | MEN1 (0.44) | PIN1MAPTPOLBALDH1A1MEN1 | |
| SCHEMBL22325849 | 0.76 | HSPB1 (0.42) | PIN1MAPTPOLBALDH1A1MEN1 | |
| SCHEMBL11649655 | 0.73 | HSPB1 (0.50) | PIN1MAPTPOLBALDH1A1MEN1 | |
| SCHEMBL22325916 | 0.70 | BRPF1 (0.42) | POLBALDH1A1KEAP1BRD4RHEB | |
| SCHEMBL11160072 | 0.70 | TDP1 (0.50) | PIN1MAPTPOLBALDH1A1MEN1 | |
| SCHEMBL5552463 | 0.70 | HSD17B10 (0.56) | PIN1MAPTPOLBALDH1A1MEN1 | |
| SCHEMBL259909 | 0.69 | TDP1 (0.54) | MAPTALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL6295009 | 0.69 | MERTK (0.50) | MAPTPOLBMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |