Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325952 | 0.93 | EPAS1 (0.46) | EPAS1ALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL22325936 | 0.89 | EPAS1 (0.43) | EPAS1ALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL22326089 | 0.86 | PDE7A (0.37) | EPAS1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22326076 | 0.86 | CA12 (0.40) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL22325857 | 0.83 | EPAS1 (0.43) | EPAS1ALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL22325934 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL22326087 | 0.78 | PDE7A (0.42) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL22325996 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL239430 | 0.76 | MEN1 (0.41) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL22325783 | 0.74 | L3MBTL1 (0.40) | ALDH1A1MAPTPOLBHSP90AA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |