Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16739068 | 0.93 | MAPT (0.43) | MAPTALDH1A1NPSR1ATMMEN1 | |
| SCHEMBL22326077 | 0.90 | MAPT (0.38) | MAPTALDH1A1NPSR1ATMMEN1 | |
| SCHEMBL22325789 | 0.87 | MAPT (0.37) | MAPTALDH1A1NPSR1ATMMEN1 | |
| SCHEMBL16738942 | 0.83 | PTGER4 (0.38) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL22325925 | 0.82 | PIN1 (0.39) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL16738867 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1NPSR1ATMMEN1 | |
| SCHEMBL22325843 | 0.79 | MAPT (0.41) | MAPTALDH1A1NPSR1ATMMEN1 | |
| SCHEMBL22326076 | 0.79 | CA12 (0.40) | MAPTALDH1A1NPSR1ATMMEN1 | |
| SCHEMBL22326090 | 0.79 | PTGER4 (0.34) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL22325879 | 0.78 | MAPT (0.35) | MAPTALDH1A1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |