Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | ARNT | P27540 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738942 | 0.91 | PTGER4 (0.38) | MAPTHTTLMNAALDH1A1TDP1 | |
| SCHEMBL22326103 | 0.87 | HCAR3 (0.36) | MAPTHTTLMNAALDH1A1TDP1 | |
| SCHEMBL1855978 | 0.86 | ALDH1A1 (0.45) | MAPTHTTLMNAALDH1A1TDP1 | |
| SCHEMBL22325730 | 0.85 | ALDH1A1 (0.44) | MAPTHTTLMNAALDH1A1TDP1 | |
| SCHEMBL22325902 | 0.78 | MAPT (0.39) | MAPTHTTLMNAALDH1A1PTGER4 | |
| SCHEMBL31577354 | 0.78 | ALDH1A1 (0.44) | MAPTHTTLMNAALDH1A1TDP1 | |
| SCHEMBL7881974 | 0.78 | ALDH1A1 (0.44) | MAPTHTTLMNAALDH1A1TDP1 | |
| SCHEMBL29860564 | 0.76 | MAPT (0.40) | MAPTHTTLMNAALDH1A1TDP1 | |
| SCHEMBL26666526 | 0.76 | MAPT (0.40) | MAPTHTTLMNAALDH1A1TDP1 | |
| SCHEMBL16739101 | 0.76 | VCP (0.40) | MAPTALDH1A1TDP1PTGER4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |