Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325958 | 0.81 | ALDH1A1 (0.34) | ALDH1A1HTTTDP1NPSR1KMT2A | |
| SCHEMBL907916 | 0.77 | TDP1 (0.45) | ALDH1A1HTTTDP1L3MBTL1TSHR | |
| SCHEMBL2841769 | 0.77 | TDP1 (0.48) | ALDH1A1HTTTDP1L3MBTL1TSHR | |
| SCHEMBL9118851 | 0.74 | TDP1 (0.43) | ALDH1A1TDP1L3MBTL1TSHRKMT2A | |
| SCHEMBL215837 | 0.72 | TDP1 (0.67) | ALDH1A1HTTTDP1L3MBTL1TSHR | |
| SCHEMBL7535846 | 0.71 | TP53 (0.46) | ALDH1A1TSHRLMNA | |
| SCHEMBL5417319 | 0.71 | KMT2A (0.55) | ALDH1A1HTTTDP1L3MBTL1KMT2A | |
| SCHEMBL22326014 | 0.70 | ALDH1A1 (0.54) | ALDH1A1HTTTDP1L3MBTL1NPSR1 | |
| SCHEMBL5478946 | 0.70 | ALDH1A1 (0.42) | ALDH1A1HTTTDP1L3MBTL1TSHR | |
| SCHEMBL1116407 | 0.69 | MEN1 (0.48) | ALDH1A1HTTTDP1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |