Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529342 | 0.77 | DRD4 (0.64) | DRD4DRD3DRD2BRD4HTR1A | |
| SCHEMBL10140 | 0.77 | BRD4 (0.60) | DRD4DRD3DRD2BRD4PARP1 | |
| SCHEMBL842410 | 0.75 | DRD1 (0.52) | DRD4DRD3DRD2HTR1ASLC6A2 | |
| SCHEMBL25386569 | 0.75 | DPP4 (0.48) | DRD4DRD3DRD2BRD4PARP1 | |
| SCHEMBL7432212 | 0.75 | PARP1 (0.53) | DRD4DRD3DRD2BRD4PARP1 | |
| SCHEMBL12894974 | 0.74 | DRD2 (0.54) | DRD4DRD3DRD2BRD4PARP1 | |
| SCHEMBL29907232 | 0.74 | DRD2 (0.54) | DRD4DRD3DRD2BRD4PARP1 | |
| SCHEMBL15724303 | 0.74 | PARP1 (0.47) | DRD4DRD3DRD2BRD4PARP1 | |
| SCHEMBL31588180 | 0.72 | DRD2 (0.52) | DRD4DRD3DRD2BRD4PARP1 | |
| SCHEMBL23123499 | 0.72 | DRD2 (0.46) | DRD4DRD3DRD2BRD4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |