Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ARNT | P27540 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325898 | 0.91 | HCAR3 (0.41) | HCAR3LMNASMN1; SMN2MAPTTP53 | |
| SCHEMBL4085561 | 0.88 | LMNA (0.41) | HCAR3LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL22325879 | 0.87 | MAPT (0.35) | HCAR3LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL22325943 | 0.86 | LMNA (0.40) | HCAR3LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL26668666 | 0.80 | HCAR3 (0.36) | HCAR3LMNASMN1; SMN2MAPTTP53 | |
| SCHEMBL1496397 | 0.79 | TP53 (0.42) | HCAR3LMNASMN1; SMN2MAPTTP53 | |
| SCHEMBL22325789 | 0.79 | MAPT (0.37) | HCAR3LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL16738942 | 0.77 | PTGER4 (0.38) | HCAR3LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL30893472 | 0.74 | KMT2A (0.39) | HCAR3SMN1; SMN2MAPTTP53GAA | |
| SCHEMBL31607327 | 0.74 | KMT2A (0.39) | HCAR3SMN1; SMN2MAPTTP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |