SCHEMBL22326113

SCHEMBL22326113

Cc1cc(N)ccc1C(c1ccc(N)cc1C)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.47
ALDH1A1 P00352 5/20 0.46
TSHR P16473 4/20 0.42
CASP1 P29466 3/20 0.42
CYP3A4 P08684 2/20 0.38
MAPT P10636 4/20 0.37
MEN1 O00255 2/20 0.37
THRB P10828 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
ALOX15 P16050 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GAA P10253 2/20 0.36
GLA P06280 1/20 0.36
POLB P06746 1/20 0.36
NR4A1 P22736 1/20 0.34
PTK2B Q14289 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22337430 0.79 TDP1 (0.43) ALDH1A1KDM4ELMNASMN1; SMN2ESR1
SCHEMBL22326132 0.78 TSHR (0.38) ALDH1A1TSHRCYP3A4MAPTKDM4E
SCHEMBL3903539 0.76 ALDH1A1 (0.56) PDE10AALDH1A1TSHRCASP1CYP3A4
SCHEMBL22044336 0.74 ALDH1A1 (0.54) PDE10AALDH1A1TSHRCASP1CYP3A4
SCHEMBL3110463 0.74 ALDH1A1 (0.54) PDE10AALDH1A1TSHRCASP1CYP3A4
SCHEMBL22326112 0.73 CYP3A4 (0.46) ALDH1A1TSHRCASP1CYP3A4MAPT
Hydrochloric Acid SCHEMBL31188372 0.72 ALDH1A1 (0.52) PDE10AALDH1A1TSHRCASP1CYP3A4
SCHEMBL30084991 0.72 ALDH1A1 (0.52) PDE10AALDH1A1TSHRCASP1CYP3A4
Hydrochloric Acid SCHEMBL3841513 0.72 ALDH1A1 (0.52) PDE10AALDH1A1TSHRCASP1CYP3A4
SCHEMBL26544526 0.72 PDE10A (0.37) PDE10AALDH1A1TSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220106444-A1 Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane CENTRAL GLASS COMPANY, LIMITED (JP) 2022-04-07 US claimed
WO-2020162408-A1 METHOD FOR PRODUCING 1,1,1-TRIFLUORO-2,2-BISARYLETHANE, AND 1,1,1-TRIFLUORO-2,2-BISARYLETHANE セントラル硝子株式会社 2020-08-13 WO claimed
US-12435185-B2 Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane CENTRAL GLASS COMPANY, LIMITED (JP) 2025-10-07 US disclosed
US-12351685-B2 Polyamide acid, polyimide, optical film, display device and production methods thereof CENTRAL GLASS COMPANY, LIMITED (JP) 2025-07-08 US disclosed
US-20230323030-A1 Polyamide, Polyamide-Imide, Derivatives of These, Optical Film, Display Device, and Production Methods Therefor CENTRAL GLASS COMPANY, LIMITED (JP) 2023-10-12 US disclosed
US-20230323030-A1 Polyamide, Polyamide-Imide, Derivatives of These, Optical Film, Display Device, and Production Methods Therefor CENTRAL GLASS COMPANY, LIMITED (JP) 2023-10-12 US disclosed
WO-2023182141-A1 EPOXY COMPOUND, EPOXY RESIN, EPOXY RESIN COMPOSITION, CURED PRODUCT, PREPREG, FIBER-REINFORCED COMPOSITE MATERIAL, PRODUCING METHODS THEREFOR, SEALING MATERIAL, SEMICONDUCTOR DEVICE, METHOD FOR SEALING SEMICONDUCTOR ELEMENT, AND METHOD FOR USING SAME AS SEALING MATERIAL セントラル硝子株式会社 2023-09-28 WO disclosed
US-20230287178-A1 Fluorinated Diamine or Salt Thereof, Method for Producing Fluorinated Diamine or Salt Thereof, Polyamide, Method for Producing Polyamide, Polyamide Solution, Cyclized Polyamide, Method for Producing Cyclized Polyamide, Insulation for High-Frequency Electronic Component, Method for Producing Insulation for High-Frequency Electronic Component, High-Frequency Electronic Component, High-Frequency Appliance, and Insulating Material for Producing High-Frequency Electronic Component CENTRAL GLASS COMPANY, LIMITED (JP) 2023-09-14 US disclosed
US-20230287178-A1 Fluorinated Diamine or Salt Thereof, Method for Producing Fluorinated Diamine or Salt Thereof, Polyamide, Method for Producing Polyamide, Polyamide Solution, Cyclized Polyamide, Method for Producing Cyclized Polyamide, Insulation for High-Frequency Electronic Component, Method for Producing Insulation for High-Frequency Electronic Component, High-Frequency Electronic Component, High-Frequency Appliance, and Insulating Material for Producing High-Frequency Electronic Component CENTRAL GLASS COMPANY, LIMITED (JP) 2023-09-14 US disclosed
US-20230287178-A1 Fluorinated Diamine or Salt Thereof, Method for Producing Fluorinated Diamine or Salt Thereof, Polyamide, Method for Producing Polyamide, Polyamide Solution, Cyclized Polyamide, Method for Producing Cyclized Polyamide, Insulation for High-Frequency Electronic Component, Method for Producing Insulation for High-Frequency Electronic Component, High-Frequency Electronic Component, High-Frequency Appliance, and Insulating Material for Producing High-Frequency Electronic Component CENTRAL GLASS COMPANY, LIMITED (JP) 2023-09-14 US disclosed
EP-4190768-A1 FLUORINATED DIAMINE OR SALT THEREOF, METHOD FOR PRODUCING FLUORINATED DIAMINE OR SALT THEREOF, POLYAMIDE, METHOD FOR PRODUCING POLYAMIDE, POLYAMIDE SOLUTION, CYCLIZED POLYAMIDE, METHOD FOR PRODUCING CYCLIZED POLYAMIDE, INSULATING MATERIAL FOR HIGH-FREQUENCY ELECTRONIC COMPONENT, METHOD FOR PRODUCING INSULATING MATERIAL FOR HIGH-FREQUENCY ELECTRONIC COMPONENT, HIGH-FREQUENCY ELECTRONIC COMPONENT, HIGH-FREQUENCY APPLIANCE, AND INSULATING MATERIAL FOR PRODUCING HIGH-FREQUENCY ELECTRONIC COMPONENT Central Glass Company, Limited (JP) 2023-06-07 EP disclosed
EP-4163319-A1 POLYAMIDE, POLYAMIDE-IMIDE, DERIVATIVES OF THESE, OPTICAL FILM, DISPLAY DEVICE, AND PRODUCTION METHODS THEREFOR Central Glass Company, Limited (JP) 2023-04-12 EP disclosed
US-20220119595-A1 Polyamide Acid, Polyimide, Optical Film, Display Device and Production Methods Thereof CENTRAL GLASS COMPANY, LIMITED (JP) 2022-04-21 US disclosed
US-20220106444-A1 Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane CENTRAL GLASS COMPANY, LIMITED (JP) 2022-04-07 US disclosed
WO-2020162408-A1 METHOD FOR PRODUCING 1,1,1-TRIFLUORO-2,2-BISARYLETHANE, AND 1,1,1-TRIFLUORO-2,2-BISARYLETHANE セントラル硝子株式会社 2020-08-13 WO disclosed
WO-2020162411-A1 POLYAMIDE ACID, POLYIMIDE, OPTICAL FILM, DISPLAY DEVICE AND PRODUCTION METHODS OF THOSE セントラル硝子株式会社 2020-08-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220106444-A1 Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane NAF1, FXR1, AFF1 PDE10A 4003/4885ALDH1A1 624/4885TSHR 1232/4885
US-12351685-B2 Polyamide acid, polyimide, optical film, display device and production methods thereof PUF60, PARG, TET3 PDE10A 1313/4885ALDH1A1 3041/4885TSHR 3460/4885
US-12435185-B2 Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane NAF1, FXR1, AFF1 PDE10A 4003/4885ALDH1A1 624/4885TSHR 1232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.