SCHEMBL22326342

SCHEMBL22326342

Cc1cnc2c(O[Al](Oc3cccc4c(C)c(C)cnc34)Oc3cccc4c(C)c(C)cnc34)cccc2c1C

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.53
CCR5 P51681 1/20 0.53
CCR8 P51685 1/20 0.53
ATP4A P20648 4/20 0.37
ATP4B P51164 4/20 0.37
NPC1 O15118 1/20 0.36
HSP90AA1 P07900 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16132474 0.83 CCR1 (0.57) CCR1CCR5CCR8ATP4AATP4B
SCHEMBL26073093 0.78 PSMD14 (0.54) CCR1CCR5CCR8NPC1HSP90AA1
SCHEMBL30423646 0.78 PSMD14 (0.54) CCR1CCR5CCR8NPC1HSP90AA1
SCHEMBL862479 0.76 CCR1 (0.68) CCR1CCR5CCR8NPC1HSP90AA1
SCHEMBL1715320 0.72 CCR1 (0.61) CCR1CCR5CCR8ATP4AATP4B
SCHEMBL16132489 0.72 CCR1 (0.61) CCR1CCR5CCR8NPC1HSP90AA1
SCHEMBL136654 0.71 CCR1 (1.00) CCR1CCR5CCR8NPC1HSP90AA1
SCHEMBL28297883 0.71 CCR1 (1.00) CCR1CCR5CCR8NPC1HSP90AA1
SCHEMBL27624147 0.71 PSMD14 (0.54) CCR1CCR5CCR8NPC1HSP90AA1
SCHEMBL2431810 0.70 CCR1 (0.59) CCR1CCR5CCR8ATP4AATP4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020162600-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2020-08-13 WO disclosed