Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 3/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26813167 | 1.00 | TRPA1 (0.42) | TRPA1TRPM8NCF1GBA1CDK9 | |
| SCHEMBL15292557 | 1.00 | TRPA1 (0.42) | TRPA1TRPM8NCF1GBA1CDK9 | |
| SCHEMBL17854859 | 1.00 | TRPA1 (0.42) | TRPA1TRPM8NCF1GBA1CDK9 | |
| SCHEMBL21138061 | 0.83 | NCF1 (0.30) | NCF1GBA1CDK9CCNT1CCNA2 | |
| SCHEMBL23559722 | 0.79 | TRPA1 (0.37) | TRPA1TRPM8 | |
| SCHEMBL13663372 | 0.79 | NCF1 (0.36) | NCF1 | |
| SCHEMBL26458056 | 0.79 | TRPA1 (0.37) | TRPA1TRPM8 | |
| SCHEMBL19286096 | 0.79 | GLB1 (0.35) | NCF1GBA1 | |
| SCHEMBL24844807 | 0.77 | TRPA1 (0.35) | TRPA1TRPM8NCF1 | |
| SCHEMBL22648430 | 0.77 | TRPA1 (0.41) | TRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10736904-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | SANOFI (FR) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10736904-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | DPYD, TYMP, DHFR | TRPA1 4478/4885TRPM8 4686/4885NCF1 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.