Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860906 | 0.84 | ADORA2A (0.47) | TP53MAPTADORA2AADORA1CYP3A4 | |
| SCHEMBL18765351 | 0.83 | MEN1 (0.43) | TP53ADORA2AADORA1MAPK1CYP3A4 | |
| SCHEMBL18765396 | 0.82 | CARM1 (0.51) | ADORA2AADORA1MAPK1CNR2F2 | |
| SCHEMBL4662763 | 0.81 | ADORA2A (0.47) | ADORA2AADORA1MAPK1L3MBTL1CNR2 | |
| Hydrochloric Acid SCHEMBL18765263 | 0.81 | CARM1 (0.50) | ADORA2AADORA1MAPK1CNR2F2 | |
| Hydrochloric Acid SCHEMBL27729074 | 0.80 | ADORA2A (0.46) | ADORA2AADORA1MAPK1L3MBTL1CNR2 | |
| SCHEMBL18765410 | 0.78 | ADORA2A (0.43) | ADORA2AADORA1MAPK1CNR2F2 | |
| SCHEMBL25587529 | 0.78 | ADORA2A (0.45) | MAPTADORA2AADORA1MAPK1CNR2 | |
| SCHEMBL15295190 | 0.76 | CYP3A4 (0.51) | ADORA2AADORA1CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL14753610 | 0.76 | CYP3A4 (0.50) | TP53MAPTMAPK1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738041-B2 | Ferroportin inhibitors | VIFOR (INTERNATIONAL) AG (CH) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738041-B2 | Ferroportin inhibitors | SLC40A1, HAMP, TFRC | TP53 3789/4885MAPT 4166/4885ADORA2A 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.