SCHEMBL22326657

SCHEMBL22326657

C=c1cccnc(=C)c(O)ccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.47
METAP2 P50579 2/20 0.47
METAP1 P53582 2/20 0.47
TSHR P16473 2/20 0.47
CHRM1 P11229 1/20 0.47
COMT P21964 1/20 0.47
ADRA1A P35348 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
ALDH1A1 P00352 6/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
KDM4E B2RXH2 9/20 0.40
ALOX12 P18054 3/20 0.40
LMNA P02545 5/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ADAMTS4 O75173 1/20 0.35
EGFR P00533 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
FYN P06241 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19413554 0.71 ALDH1A1 (0.42) MMP2METAP1TSHRHDAC8ALDH1A1
SCHEMBL25475023 0.69 GABRA1 (0.39) TSHRLMNAHPGDCA1CA2
SCHEMBL764220 0.69
SCHEMBL693562 0.67
SCHEMBL18868634 0.67 ALDH1A1 (0.39) MMP2METAP1TSHRHDAC8ALDH1A1
SCHEMBL687180 0.66 KDM4E (0.55) MMP2METAP2METAP1TSHRCHRM1
SCHEMBL29769309 0.66 KDM4E (0.55) MMP2METAP2METAP1TSHRCHRM1
SCHEMBL13888459 0.66
SCHEMBL103661 0.66
SCHEMBL29366238 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10738203-B2 Curing accelerator for oxidatively polymerizable unsaturated resin, printing ink and coating material DIC CORPORATION (JP) 2020-08-11 US disclosed