Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CCR1 | P32246 | 3/20 | 0.38 |
| ▸ | CCR5 | P51681 | 3/20 | 0.38 |
| ▸ | CCR8 | P51685 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19413554 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL24702543 | 0.83 | KDM4E (0.38) | ALDH1A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL21440403 | 0.72 | ALOX12 (0.39) | ALDH1A1KDM4ELMNAHIF1APOLB | |
| SCHEMBL19413665 | 0.70 | — | — | |
| SCHEMBL24702544 | 0.69 | EGFR (0.40) | KDM4ECYP1A2CYP3A4ATMCYP2D6 | |
| SCHEMBL19466036 | 0.68 | LMNA (0.56) | ALDH1A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL23011617 | 0.67 | KDM4E (0.41) | ALDH1A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL22326657 | 0.67 | MMP2 (0.47) | ALDH1A1KDM4ELMNAHIF1AMETAP1 | |
| SCHEMBL21846145 | 0.67 | KDM4E (0.30) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL20273121 | 0.64 | GABRA1 (0.34) | LMNAHIF1ACYP1A2BLMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190288220-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-09-19 | — | — | US | disclosed |
| EP-2428504-B1 | Small molecule inhibitors of the pleckstrin homology domain and method for using same | UNIV TEXAS (US) | 2017-05-17 | — | — | EP | disclosed |