SCHEMBL22328876

SCHEMBL22328876

Nc1cc2ccc(-c3ccccc3)cc2cc1C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.71
KDM4E B2RXH2 2/20 0.55
KMT2A Q03164 2/20 0.55
GFER P55789 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
ACMSD Q8TDX5 4/20 0.53
IKBKB O14920 1/20 0.51
HNF4A P41235 2/20 0.50
MCL1 Q07820 2/20 0.50
DHFR P00374 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN2A Q12879 1/20 0.50
GRIN2B Q13224 1/20 0.50
GRIN2C Q14957 1/20 0.50
PPM1B O75688 1/20 0.49
ESR1 P03372 2/20 0.49
ESR2 Q92731 2/20 0.49
DCLRE1A Q6PJP8 1/20 0.45
DCLRE1B Q9H816 1/20 0.45
HSD17B10 Q99714 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14503721 1.00 IDO1 (0.71) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL22328897 0.89 IDO1 (0.65) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL197490 0.84 IDO1 (1.00) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL29475880 0.84 IDO1 (1.00) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL8006518 0.84 IDO1 (1.00) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL569383 0.81 ACMSD (0.68) ACMSDHNF4AMCL1DHFRGRIN2D
SCHEMBL2790839 0.81 KMT2A (0.72) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL2575452 0.80 PPM1B (0.71) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL30456877 0.80 PPM1B (0.71) IDO1KDM4EKMT2AGFERRXFP1
SCHEMBL2246915 0.80 KMT2A (0.84) IDO1KDM4EKMT2AGFERRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3696155-B1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KK (JP) 2022-06-29 EP disclosed
EP-3696155-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2020-08-19 EP disclosed
US-20200255358-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2020-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200255358-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CCNL2, MCM4, CCNT1 IDO1 1665/4885KDM4E 1755/4885KMT2A 2067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.