SCHEMBL2575452

SCHEMBL2575452

Nc1cc(-c2ccccc2)ccc1C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.71
ACMSD Q8TDX5 3/20 0.63
HNF4A P41235 2/20 0.63
IKBKB O14920 1/20 0.59
KDM4E B2RXH2 3/20 0.59
KMT2A Q03164 3/20 0.59
GFER P55789 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
MCL1 Q07820 2/20 0.58
DHFR P00374 1/20 0.58
ALDH1A1 P00352 4/20 0.57
HPGD P15428 3/20 0.57
HSD17B10 Q99714 2/20 0.57
MEN1 O00255 2/20 0.57
GAA P10253 2/20 0.57
ALOX15 P16050 2/20 0.57
USP2 O75604 1/20 0.57
LMNA P02545 1/20 0.57
HSP90AA1 P07900 1/20 0.57
MAPT P10636 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30456877 1.00 PPM1B (0.71) PPM1BACMSDHNF4AIKBKBKDM4E
SCHEMBL23499274 0.94 PPM1B (0.79) PPM1BACMSDHNF4AIKBKBKDM4E
SCHEMBL29908977 0.94 PPM1B (0.79) PPM1BACMSDHNF4AIKBKBKDM4E
SCHEMBL29436316 0.92 PPM1B (0.75) PPM1BACMSDHNF4AIKBKBKDM4E
SCHEMBL710309 0.92 PPM1B (0.75) PPM1BACMSDHNF4AIKBKBKDM4E
SCHEMBL17177763 0.88 PPM1B (0.70) PPM1BACMSDHNF4AIKBKBKDM4E
SCHEMBL30314350 0.88 PPM1B (0.70) PPM1BACMSDHNF4AIKBKBKDM4E
SCHEMBL13522904 0.87 PPM1B (0.56) PPM1BACMSDHNF4AIKBKBKDM4E
SCHEMBL3793566 0.86 IKBKB (0.73) PPM1BACMSDHNF4AIKBKBKDM4E
SCHEMBL6851164 0.86 PPM1B (0.74) PPM1BACMSDHNF4AKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025100475-A1 COMPOSITION FOR IMAGE RECORDING AND METHOD FOR PRODUCING SAME キヤノン株式会社 2025-05-15 WO disclosed
CN-116253898-B Metal-organic frame material for optical wireless communication, ligand and application thereof 吉林省卓材新研科技有限公司 2023-08-01 CN disclosed
CN-116253898-A Metal-organic frame material for optical wireless communication, ligand and application thereof 吉林省卓材新研科技有限公司 2023-06-13 CN disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
CN-113396145-A PFKFB3 inhibitors and uses thereof 盖罗发现有限责任公司 2021-09-14 CN disclosed
US-20200148634-A1 ACLY INHIBITORS AND USES THEREOF Nimbus Artemis, Inc. 2020-05-14 US disclosed
WO-2020080979-A1 PFKFB3 INHIBITORS AND THEIR USES GERO DISCOVERY LIMITED LIABILITY COMPANY (RU) 2020-04-23 WO disclosed
EP-3143007-B1 ANTIBACTERIAL QUINAZOLINE-4(3H)-ONE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2018-07-11 EP disclosed
CN-107849022-A SUBSTITUTED QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF 亚瑞克西斯制药公司 2018-03-27 CN disclosed
WO-2010087430-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF 富山化学工業株式会社 (JP) 2010-08-05 WO disclosed
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed
CN-101511783-A N-biaryl (hetero) arylsulphonamide derivatives useful in the treatment of diseases mediated by lymphocytes interactions NOVARTIS AG (CH) 2009-08-19 CN disclosed
US-20090105474-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-04-23 US disclosed
EP-1860098-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-11-28 EP disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed
CN-1185399-C Allochroic glass and window made of the glass LIN TING (CN) 2005-01-19 CN disclosed
US-6727250-B2 ADMINISTERING COMPOUNDS SUCH AS TRANS-3-(NAPHTH-2-YL)-BUT-2-ENOIC ACID-N-(2-CARBOXY-PHENYL)-AMIDE OR LIKE FOR THERAPY OF CONDITIONS ASSOCIATED WITH INCREASED TELOMERASE ACTIVITY, E.G. TUMOUR DISEASES BOEHRINGER INGELHEIM PHARMA KG (DE) 2004-04-27 US disclosed
US-20020099089-A1 Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and preparation BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-07-25 US disclosed
US-6362210-B1 ANTITUMOR, ANTICANCER AGENT BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES PFKFB3, PFKFB4, PFKFB1 PPM1B 1219/4885ACMSD 3939/4885HNF4A 744/4885
US-20020099089-A1 Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and preparation TERT, NAT1, POT1 PPM1B 1608/4885ACMSD 604/4885HNF4A 1516/4885
US-20200148634-A1 ACLY INHIBITORS AND USES THEREOF ACLY, ATP5ME, ATP5MG PPM1B 2631/4885ACMSD 829/4885HNF4A 1977/4885
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP26, MMP11 PPM1B 4343/4885ACMSD 58/4885HNF4A 2172/4885
US-20090105474-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP11, MMP3 PPM1B 4641/4885ACMSD 344/4885HNF4A 1746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.