SCHEMBL22328895

SCHEMBL22328895

CC1(C)OB(c2ccc3c4c(cccc24)-c2c-3c(-c3ccccc3F)c3ccccc3c2-c2ccccc2F)OC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 2/20 0.36
BTK Q06187 2/20 0.36
LPL P06858 2/20 0.31
LIPG Q9Y5X9 2/20 0.31
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21888321 0.86 KDM4E (0.33) JAK2BTKLPLLIPGCRHBP
SCHEMBL22328871 0.85 LPL (0.43) JAK2BTKLPLLIPGCRHBP
SCHEMBL30169934 0.84 LIPG (0.42) LPLLIPGCRHBPCRHR2KEAP1
SCHEMBL762751 0.84 LIPG (0.42) LPLLIPGCRHBPCRHR2KEAP1
SCHEMBL21888323 0.84 LPL (0.34) JAK2BTKLPLLIPG
SCHEMBL21888373 0.82 LPL (0.38) LPLLIPG
SCHEMBL30040842 0.82 KEAP1 (0.46) JAK2BTKLPLLIPGCRHBP
SCHEMBL961673 0.82 KEAP1 (0.46) JAK2BTKLPLLIPGCRHBP
SCHEMBL29709221 0.82 KEAP1 (0.46) JAK2BTKLPLLIPGCRHBP
SCHEMBL21888372 0.81 JAK2 (0.40) JAK2BTKLPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200255358-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2020-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200255358-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CCNL2, MCM4, CCNT1 JAK2 1830/4885BTK 3827/4885LPL 3322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.